Argentina's Top Startups to Watch for 2026 according to Cuantico VP

Argentina is experiencing a pivotal moment for innovation and venture capital. The startup ecosystem is showing signs of recovery and optimism after years of macroeconomic challenges, marked by the consolidation of early-stage investment, increasing professionalization, and the emergence of new verticals such as biotechnology, artificial intelligence, agtech, digital health, and fintech.

According to Cuantico VP data, the Argentine market was one of the few Latin American ecosystems to show signs of recovery in 2024. In fact, the largest venture capital round in the region was led by the Argentine fintech Ualá, which raised US$300 million in its Series E.

Greater economic openness and fewer restrictions are attracting international funds, especially in sectors where Argentina is globally competitive. This new generation of startups is defined by their global vision, operational efficiency, and strong focus on product and traction, positioning themselves to lead the next decade of regional innovation.

A “Startup to Watch” is a company backed by the talent, vision, and resources needed to transform industries. This list highlights the potential of Argentine startups already revolutionizing diverse sectors, from Fintech to Biotechnology.

Biotechnology & AgTech

Puna Bio

Founders: Franco Martínez Levis (CEO), Elisa Violeta Bertini, Carolina Belfiore and María Eugenia Farías.

Puna Bio develops groundbreaking biological inputs from extremophile microorganisms native to the Argentine Puna to improve agricultural yields, restore degraded soils, and reduce carbon emissions.

The startup closed its Series A led by Corteva Catalyst, with the historic participation of the Gates Foundation—their first investment in an Argentine startup—alongside At One Ventures, SP Ventures, Dalus Capital, Grid Exponential, and Builders VC.

Its products, Kunza and Kanzama, are already deployed across more than 800,000 acres in the United States, Brazil, Paraguay, and Argentina, with plans to expand to Africa and other regions.

Calice AI

Founders: Ramiro Olivera (CEO), Esteban Hernando, Andrés Rabinovich, Pablo Romero (CFO/COO)

Calice AI is an Artificial Intelligence platform for agribusiness that uses virtual field trials to predict crop yield and quality, reducing the need for physical tests by up to 80%.

Raised a $2.5 million seed round led by Astanor, with participation from Draper Cygnus, Xperiment Ventures, AIR Capital, Innventure, and GrainCorp Ventures. The company forecasts $800,000 in revenue for 2025 and has validated results in corn, soybeans, barley, wheat, and rice.

Nunatak Biotech

Founders: Julia Mensa (CEO), Martha Martorell (Microbiology Specialist), Francisco Massot (Bacteriology and Phytoremediation Specialist).

Nunatak Biotech is a pioneering biotechnology company focused on natural solutions for soil restoration using plant-microorganism associations with Antarctic extremophiles. Their initial proposal combines Antarctic microorganisms with fast-growing species like ryegrass to turn degraded soils into living ecosystems.

Raised $400,000 in pre-seed and has established agreements with Green4Growth and submitted proposals to GRIDX, positioning itself for partnerships with seed companies and agricultural producers.

Giraffe Bio

Founders: Alejandro Buffo Sempé (CEO), Juan Pablo Fernández (PhD)
Investors: StartUP Chile, AIR Capital, Indie Bio, SOSV

Giraffe Bio develops AI-designed biomolecules to improve the extraction of critical minerals like copper and lithium in mining operations. Their hardware-biotech-AI platform generates proprietary datasets on metal-biomolecule interactions, training machine learning models to design highly selective biomolecules.

The company has demonstrated a 20% increase in copper recovery in flotation processes and reduced lithium extraction from months to hours, raising $1.136 million to date.

Health, Diagnostics and MedTech

Oncoliq

Founders: Adriana De Siervi and Marina Simian
Investors: Air Capital, Dim Centros de Salud, Endurance28, Draper University Ventures, WIT Angel Club and Sah-Lood.

Oncoliq revolutionizes early cancer detection with liquid biopsy technology that analyzes microRNAs from blood samples, achieving 91% sensitivity in clinical validations. The startup is running pilot studies with 1,000 volunteers for breast cancer detection and collaborating with the Central Military Hospital and Argentina’s National Cancer Institute.

Their platform combines molecular biology with machine learning for non-invasive, low-cost screening.

Motivia

Founders: Juan Cruz Forgioni (CEO), Maximiliano Abrutsky (ex-CTO Betterfly), Pablo Kruls (CBO), Lucas Gamarnik
Investors: Alaya Capital, DQVentures, Malbec Ventures, Sancor Seguros Ventures

Motivia is a healthtech platform combining AI and behavioral sciences to improve adherence for chronic disease patients. Closed a $1.2 million pre-seed round led by Alaya Capital, after achieving an 87% reduction in rehospitalizations and a 44% reduction in mortality for heart failure patients.

With over 2,000 active monthly users, mainly women aged 60–65, it plans to expand to Mexico and Colombia in 2025.

Avedian

Founders: Guillermo Tabares, Facundo Tabares (CFO), Pablo Tabares (COO)—third-generation health entrepreneurs.

Avedian is a comprehensive health records management platform with predictive AI, serving three verticals: Hosdatia (hospitals), Insuria (insurance), and Pharmia (laboratories). Closed a $1 million Pre-Series A round led by Meet Capital.

It is one of only three companies worldwide that has standardized health data internationally, operating in five countries and partnering with Globant Healthcare & Lifesciences AI.

Artificial Intelligence, SaaS & Productivity

Patagon AI

Founders: David Grandes (CEO), Mariano Rey, Cristian Adamo, Roberto Guerrero.

Patagon AI is an Ecuadorian-Argentine platform of AI agents for automating sales and marketing processes, achieving up to 400% increase in conversions.

Raised $1.1 million led by OneVC (Brazil) and 17Sigma (Argentina). Operates in Colombia, Brazil, Mexico, Chile and Argentina, serving clients like Autos OK, Alvarez Bravo, and Humana S.A., projecting $2 million ARR for 2025.

Takenos

Founders: Lucas Posada, Joaquín Herrera, Francisco Goulu, Simón Bouché

Takenos is a crypto-fiat digital wallet for Latin American freelancers enabling international payments and multi-currency management. Closed a $5 million seed round co-led by Variant and Lattice Fund—the first investment from these Silicon Valley funds in Latin America—with participation from Reverie, North Island Ventures, Refract VC, and others.

Processed more than $500 million in transactions through strategic partnerships with Mastercard, Visa, Fireblocks, and Bridge.

Fintech & Cross-Border Payments

Remitee

Founders: Sergio Saravia (CEO), Nicolas Ignacio Zamudio, Eduardo Hamel.
Investors: Krealo, Copec Wind Ventures, Soma Capital, Redwood Ventures, Latitud, Algorand.

Remitee is a B2B2C remittance infrastructure platform enabling banks, fintechs, and retailers to integrate instant cross-border payments. Raised $20 million led by Krealo (Peru) to expand its infrastructure, which already connects 42 countries.

Its technology is used by more than 40 institutions including Santander, Banco Galicia, Banco Estado, BCP, Yape, Falabella, Remitly, and MoneyGram, processing a share of the $150 billion in annual remittances to Latin America.

Mobility & Services

Autonomy

Founder: José Trusso (CEO, ex-Deutsche Bank, JP Morgan, ex-Ministry of Finance).

Autonomy is a mobility fintech platform with a rent-to-own model that acquires vehicles to rent to drivers with a purchase option after 12–18 months. Raised $1.5 million in a round led by Gabriel Martino (ex-CEO HSBC Argentina, founder BFLinvest) and Murchison Ventures. With 200 cars in operation and $2 million raised in total, it aims for 1,000 vehicles by 2025 with a projected $10 million investment.

Vaitty (formerly Rapihogar)

Founders: Mariano Buxdorf (CEO and Co-founder).

Vaitty (Formerly Rapihogar) is a digital platform for home and personal wellness services, connecting everything from cleaning and maintenance to wellness solutions. Has scaled to over 80,000 services managed annually, expanding into data-driven home services and personalized wellness solutions.

The Future of the Argentine Ecosystem

These startups represent the cutting edge of Argentine innovation for 2026, demonstrating an ability to attract top-tier international capital, build globally competitive products, and tackle real-world problems with frontier technology. Their collective success confirms Argentina’s continued position as one of the most resilient entrepreneurial ecosystems in Latin America, readying itself for a new decade of sustained growth, regional expansion, and global-impact solutions.

The sectoral diversity—from biotechnology to cross-border Fintech, applied AI, and predictive healthtech—showcases the breadth of Argentine talent and its capacity to innovate across multiple verticals simultaneously.